IL6 and juvenile polyposis syndrome: Ackmann et al. [39] found that Interleukin-6 (IL-6) combined with D-dimer was slightly more specific than CRP combined with D-dimer for the diagnosis of PJI, and both combinations were more specific than D-dimer alone for the diagnosis of PJI, but both were less sensitive than D-dimer (860 ng/ml).