In the largest data set so far on miRNAs as liquid biomarkers in iGCT, we underlined the utility of miR-371a, miR-372, miR-367 and miR-302d in patient serum for diagnosis of iGCT, a result particularly noteworthy in germinoma patients negative for other biomarkers, such as AFP and ß-HCG. This evidence concerns the gene AFP and germinoma.