OTULIN and autoinflammation, panniculitis, and dermatosis syndrome, autosomal recessive: Thus, the degree of impairment of linear chain hydrolysis might correlate with ORAS severity and these data could provide the molecular explanation why the patient of this study was supposedly asymptomatic until the age of 7 years while ORAS patients carrying the homozygous OTULIN variant p.L272P diseased already after birth.