In addition, we quantified DIRAS3 expression levels in several human lung adenocarcinoma cell lines (A549, H1299, HCC827, and PC-9) and human lung squamous cell carcinoma cell lines (H520 and H1270), and subsequent results illustrated that DIRAS3 expressions were diminished in A549, H1299, HCC827, PC-9, H520, and H2170 cells compared to those in BEAS-2B cells. This evidence concerns the gene DIRAS3 and lung adenocarcinoma.