NFKB1 and cancer: NF‐κB plays important roles in cancer progression by directly targeting a variety of genes or crosslinking to other signaling pathways.[28] However, the response of NF‐κB activation could be different in various cells, despite receiving the same stimulus.[8, 29] We demonstrated that F. nucleatum‐activated NF‐κB regulates distinct lipid metabolisms in CCSCs and regular CRC cells.