Consequently, these alterations in cytokine production resulted in a strong imbalance between pro- and anti-inflammatory cytokine expression in IBD, as evidenced by increased ratios of IFN-γ+, IL-17+ and IL-17+/IFN-γ+ to IL-10+ memory CD4+ T cells in CD and UC patients (Fig. 5d). The gene discussed is CD4; the disease is inflammatory bowel disease.