Among the inflammatory cytokines, the interleukins IL-1β, IL-6, IL-8, IL-10 and TNF-α are the most studied regarding the development and progression of tendon diseases, as well as in healing and exercise response [16–18], being released by stromal and immunoregulatory tendon cells in presence of tissue damage and mechanical stress, altering local cells phenotype [17]. Here, CXCL8 is linked to disease of the tendon.