Among the 103 eQTL genes of the TF binding-disrupting SNPs, four (AMT, DALRD3, GPNMB, and RHOBTB2) showed significantly varied mRNA levels (corrected, q < 0.05) in brains of PD cases compared with controls (Additional file 1, Table S14) [20], suggesting that these TF binding-disrupting SNPs may confer PD risk through regulating these genes. The gene discussed is AMT; the disease is Parkinson disease.