AMT and Parkinson disease: For AMT and DALRD3, the results of eQTL analysis and reporter gene assays were consistent (i.e., the C allele was associated with lower reporter gene activity and expression of AMT and DALRD3), suggesting this SNP may contribute to PD risk by regulating the expression of AMT and DALRD3. We further performed differential expression analysis and found that the expression of AMT (P = 2.13 × 10−3) and DALRD3 (P = 2.93 × 10−3) were significantly downregulated in brains of PD cases compared with controls.