Among them, 11 switch genes (i.e., CENPN, LRP8, DSCC1, CTPS, RCOR2, GINS4, TUBA1C, PRAME, SLC7A11, CDCA7, GSDMC) appeared to be an unfavourable prognostic gene (Fig 2), suggesting that their higher expression could be associated with poorer BC patients’ overall survival (OS). The gene discussed is CDCA7; the disease is breast cancer.