ITGAM and acute myeloid leukemia: Unlike the blue cluster with high monocytic differentiation, and the green cluster with poor monocytic differentiation, the AML samples 2 and 5 of the red cluster included both positive and negative populations of CD11b which is a common granulocytic and monocytic maturity marker, a feature observed in all MDS samples as well (Appendix 1—figure 27).