We therefore aimed to analyze the distribution and localization of vitamin D‐activating and degrading enzymes CYP27B1 and CYP24A1 (25‐Hydroxyvitamin D‐24‐hydroxylase) and VDR in post‐mortem human brain (Braak stage 6) of PD patients. The gene discussed is CYP27B1; the disease is Parkinson disease.