It has been reported to decrease the activity of cyclooxygenase-2 (COX-2) and nitric oxide synthase (NOS) 27, suppress levels of proinflammatory cytokines and chemokines, reduced the adhesion of eosinophils to tracheal epithelial cells 28, and inhibit sepsis-induced acute lung injury 26, 29. This evidence concerns the gene PTGS2 and Sepsis.