OXT and Central diabetes insipidus: Many other approved peptide drugs are also derived from natural hormones1, including octreotide, a somatostatin mimic peptide drug, used for the treatment of growth hormone producing tumors and pituitary tumors56,57; desmopressin, an 8-Arg-vasopressin mimicking peptide drug, used for diabetes insipidus and nocturia58; carbetocin, an oxytocin homologue used to treat amenorrhea59 and atosiban, an oxytocin antagonist for suppressing premature labor60.