Finally, we demonstrated that insulin-related gene sets may be pleiotropic for neuropsychiatric disorders (i.e., AN, ADHD, ASD, BD, OCD, and SCZ) and somatic insulinopathies, suggesting that the cumulative effect of genetic variability within insulin-related gene sets on the investigated neuropsychiatric disorders except for AN and ADHD is in the opposite direction to the effect on somatic insulinopathies. Here, INS is linked to Behcet disease.