INS and attention deficit-hyperactivity disorder: Finally, we demonstrated that insulin-related gene sets may be pleiotropic for neuropsychiatric disorders (i.e., AN, ADHD, ASD, BD, OCD, and SCZ) and somatic insulinopathies, suggesting that the cumulative effect of genetic variability within insulin-related gene sets on the investigated neuropsychiatric disorders except for AN and ADHD is in the opposite direction to the effect on somatic insulinopathies.