BAX and Alzheimer disease: It alleviates the cognitive deficits in the senescence accelerated mouse prone 8 (SAMP8) Alzheimer’s disease (AD) animal model by inhibiting the formation of amyloid plaques through the downregulation of amyloid-beta 1-42 (Aβ1-42), suppression of neuronal death as well as promoting apoptosis by increasing the B-cell lymphoma 2 (Bcl-2)/Bax ratio [16].