HPN and hepatocellular carcinoma: Low HPN expression was associated with worse prognosis in HCC (OS: HR = 0.54, 95% CI = 0.38 to 0.76, P = 0.00044; PFS: HR = 0.68, 95% CI = 0.51 to 0.91, P = 0.0094; Fig. 5c, d).