CYP2E1 and metabolic dysfunction-associated steatohepatitis: This speculation is supported by previous reports from other groups [9, 35–39] as well as ours [16, 17, 40] that increased CYP2E1 activity is closely associated with oxidative stress, inflammation, and inflammation-related diseases like nonalcoholic steatohepatitis (NASH), hepatofibrosis, HCC, ovarian cancer, and so on.