Regarding the presence of laboratory abnormalities supporting APS, two subjects had only the lupus anticoagulant, 10 subjects had both LAC and IgG anticardiolipin antibody, 8 had LAC with IgM ACL antibodies, and 9 had LAC with both IgM and IgG ACL antibodies. This evidence concerns the gene ACLY and autoimmune polyendocrinopathy.