Then, we found that downregulation of METTL14 showed no association with clinicopathological characteristics including pathological stage and TNM stage in patients with GC (Supplementary Table S2), however, Kaplan–Meier analysis uncovered that the patients with low-METTL14 expression indicated poor overall survival as compared with those with high-METTL14 expression (Fig. 1E, P = 0.042). The gene discussed is METTL14; the disease is gastric cancer.