GC and colorectal cancer: Interestingly, we found similar expression patterns of exosomal circLPAR1 in many cancers, including GC, BRCA, BLCA, CESC, KIRC, and LUAD (P > 0.05; Fig. 3C and Table S5), and these patterns were all notably different from the pattern in colorectal cancer (P < 0.001; Fig. 3C).