In contrast, Xing et al. highlighted that miR-4521 acted as an inhibitor in regulating STAD tumor metastasis and EMT via inhibiting IGF2 and FOXM1 [23], and Ye et al. suggested that inhibited miR-7 facilitated STAD progression, and was related to the poor clinical outcomes [24]. Here, IGF2 is linked to gastric adenocarcinoma.