NECTIN4 and renal pelvis/ureter urothelial carcinoma: Contrarily, Tomiyama et al. showed a Nectin-4 expression in 65/99 (65.7%) of UTUC samples with a predominant low-medium expression profile (1+, 31.3%; 2+, 24.2%; and 3+, 10.1%) [15], confirming, as in our data, a lower expression of Nectin-4 In UTUC in respect to LTUC, and a partially different biological profile.