The results showed that maternal diabetes (STZ/VEH) significantly decreased the mRNA levels of RORA, CYP19A1 and SOD2 (P < 0.0001) compared to the CTL/VEH group; MnTBAP treatment (STZ/MnTBAP) completely, while STZ/SR1078 treatment partly (P < 0.01), reversed this effect (see Fig. 4a). This evidence concerns the gene SOD2 and diabetes mellitus.