Association analysis displayed a negative relationship between the expression extents of miR-1298-5p and E2F1 in synovial tissue samples of RA patients (Figure 4e, r = −0.6673, p < 0.001), while a positive relationship between the expression extent of OSER1-AS1 and E2F1 was found (Figure 4f, r = 0.7297, p < 0.001). This evidence concerns the gene E2F1 and rheumatoid arthritis.