The early diagnosis of such infections and timely targeted antibiotic therapy are thus pivotal for limiting morbidity rates, reducing costs, and improving patient condition; however, early diagnoses of bacterial infections remain challenging as conventional laboratory markers to detect them, such as white blood cell count, C-reactive protein (CRP) levels, and erythrocyte sedimentation rate, are often influenced by uremia, extracorporeal treatment, or immunosuppressive drugs [2,3]. This evidence concerns the gene CRP and bacterial infectious disease.