Ziying Li et al. [48] established a chitosan-based nanocomplex CE7Q/CQ/S to deliver molecular-targeted drug erlotinib (Er), Survivin shRNA-expressing plasmid (SV), and Cy7 for simultaneous NIR fluorescence imaging and monitored chemo/gene/photothermal tri-therapies therapy for NSCLC bearing epidermal growth factor receptor (EGFR) mutations. This evidence concerns the gene EGFR and non-small cell lung carcinoma.