Rutin, as a multifunctional biological molecule, can treat and prevent Alzheimer’s disease by regulating various pharmacological mechanisms, such as antioxidant mechanisms, mechanisms related to metal chelation, anti-inflammatory mechanisms, Aβ mechanisms, formation of Aβ, Aβ aggregation and toxicity, and acetyl cholinesterase (AChE) mechanisms [158]. This evidence concerns the gene ACHE and early-onset autosomal dominant Alzheimer disease.