Evidence has revealed that YZQXF alleviates cognitive deficits by increasing the levels of LC3II/LC3I and Beclin1, remarkably activating 4EBP1 and inhibiting the phosphorylation of mammalian target of rapamycin (mTOR) at Ser2448 in early-onset AD mice [24]. The gene discussed is MTOR; the disease is Alzheimer disease.