ACE2 and infection: This molecule acts on at least two mechanisms: the reduction of the number of infected cells (through a down-regulation of the expression of the main mediators of the infection: ACE2, TMPRSS2 and NRP1), and the inhibition of the cytokine storm (through an inhibition of pro-inflammatory cytokine release mediated by Nfr2 activation and Nf-Kb inhibition).