HMGB1 and COVID-19: The results from RNA sequencing showed that FBA is also able to modulate several other mechanisms involved in SARS-CoV-2 infection, such as HMGB1, which is involved in virus replication [23], IRAK1 [24], CD14, a target to control the inflammation of COVID-19 [25] and TLR4, another receptor for the SARS-CoV-2 spike protein [26].