Despite the fact that the genistein mechanism of action seems to be related mainly to controlling the opening of the CFTR chloride channel [91], in a study carried out by Lord et al. in which, over a period of 45 days, mice were fed ad libitum a diet containing genistein (600 mg/kg diet) or colyte-genistein, increased body weight of male F508del-CF mice and improved survival rate of F508del-CF female mice in the absence of laxatives were observed [94]. This evidence concerns the gene CFTR and cystic fibrosis.