In fact, the present study revealed that vaginal mucosa and endometriotic cells responded to increased levels of IL-6, IL-8, IL-1β, and TNF-α when challenged by Candida albicans or by LPS, and these cells present a pivotal role in the inflammatory process in endometriosis and leiomyoma. The gene discussed is CXCL8; the disease is leiomyoma.