CAT and Glucose intolerance: Aging has been shown to be associated with heart and skeletal muscle dysfunction and glucose intolerance, but these were suppressed by SFN, which reduced 8OHdG (8-hydroxy-2-deoxyguanosine) and muscle myostatin expression—markers of skeletal muscle oxidation and apoptosis respectively—as well as upregulated expression of antioxidant and anti-electrophilic genes (SOD1, SOD2, CAT-catalase, Nrf2, and Akr3- aldo-keto reductase 3) [66].