Some authors stressed the need for substances with multiple mechanisms of action since AD is of multifactorial aetiology (amyloid-β (Aβ) cascade, protein misfolding, tau hyperphosphorylation, inflammation, gene mutation, mitochondrial dysfunction, and oxidative stress) and here plants offer a huge diversity of phytochemicals, which may address multiple aetiologies [231]. This evidence concerns the gene MAPT and Alzheimer disease.