KCNQ1OT1 and cancer: Additionally, KCNQ1OT1 is involved in several disorders, including heart disease, cerebral ischemic stroke, atherosclerosis, pyroptosis, and various cancers (gastric, ovarian, and colorectal) by binding to various miRNAs (for example, miR-760, miR-200a, miR-452-3p, miR-320a, miR-701-3p, and miR-2054), all of which regulate the expression of their target genes [7,8,9,10,11,12,13].