Remarkably, the Ser1231 site is a multitarget residue that can be also phosphorylated by the extracellular signal-regulated kinase 1 and 2 (ERK1/2) [29]—whose expression and activation are enhanced upon transient cerebral ischemia [30]—and additionally, by the cyclin-dependent kinase 1 (Cdk1) [31,32]. Here, MAPK3 is linked to transient ischemic attack.