SPDL1 and neoplasm: However, the expression status of SPDL1 was not associated with any examined clinicopathological data listed in Table 1 (p > 0.05), including age, gender, grading, primary tumor (pT) classification, regional lymph node (pN) status, distant metastasis (pM) status, AJCC TNM stage, vascular invasion, perineural invasion, resection margins, and primary tumor location.