Consistent with their relationship in the correlational distance data (blue line in Figure 4E), p-CREB (Ser133) is a potential neuroprotective biomarker [35,36,37,38], whereas p-ATF2 (Thr71) was considered as a fetal brain hemorrhage biomarker under the VIR condition [21]. This evidence concerns the gene CREB1 and intracranial hemorrhage.