FKBP52 protein expression is strongly decreased in the frontal cortex of AD and FTLD-Tau brains (Frontotemporal Lobar Degeneration linked to a point-mutation of the Tau gene (i.e Tau-P301L)) [139] whereas no indication has been provided to date concerning the expression of FKBP52 in affected brain regions of PD patients. The gene discussed is MAPT; the disease is Alzheimer disease.