Using MgTx, the modulatory role of Kv1.3 was established in proliferation of neural progenitor cells [28], damage-induced secretion of pro-inflammatory cytokines and chemokines in brain tissue [29], and in the production of reactive oxygen species by microglial cells related to the pathogenesis of Alzheimer’s disease [30]. The gene discussed is KCNA3; the disease is Alzheimer disease.