The inhibition of GSK-3 α/β using the CHIR99021 GSK-3 α/β inhibitor was shown to enhance the ratio of LC3 A/B-II to LC3 A/B-I and effectively decrease p62 expression in epithelioid sarcoma cells [11], suggesting that induction of autophagy occurs in epithelioid sarcoma cells [11]. The gene discussed is MAP1LC3A; the disease is epithelioid sarcoma.