Several studies have established that flavonoids such as EGCG, resveratrol, curcumin, genistein, quercetin, luteolin, sulforaphane, etc., deter cancer growth, reduce inflammation, improve anti-oxidation and induce apoptosis by modulating various apoptotic proteins and signalling pathways such as MAPK, NF-kB, PI3K/Akt, Wnt, etc. [8,9,10,11]. Here, PIK3CA is linked to cancer.