Intrinsic subtypes such as hormone-receptor-dependent (progesterone receptor (PR) and oestrogen receptor (ER)) expression), human epidermal growth factor receptor 2 (HER2) positive, and triple negative breast cancer (TNBC), which is PR, ER and HER2 negative, are clinically relevant because their therapeutic stratification depends on molecular diagnosis [2]. This evidence concerns the gene ERBB2 and triple-negative breast carcinoma.