ALDH18A1 and Dysarthria: Studies by Coutelier et al. [30] and Seri et al. [31] showed 10q23.3-q24.2 with heterozygous mutation in Aldehyde Dehydrogenase 18 Family member A1 (SPG9A/ALDH18A1) is linked to spinocerebellar ataxia with least expressed features such as cataract and dysarthria in people, causing the onset to occur anywhere from adolescence to adulthood.