NFKB1 and disease of the tendon: Tendinopathies are mostly come along with inflammation-associated destruction of ECM, leading to tendon destruction and decreased biomechanical functionality, whereby pro-inflammatory cytokines as well as catabolic enzymes are mostly up-regulated by NF-κB activity [34,35], which has been previously shown to be suppressed by CA in tumor cells and cells of the connective tissue, but not in tenocytes yet [49,51,52,53].