Hence, we sorted macrophages from Tg(mpeg1:eGFP)gl22 larvae, treated or not treated with HP-NAP, 4 d after the transplantation of melanoma cells (Supplementary Figure S2) and we determined the expression pattern of pro-inflammatory (il-1β and il-6) and immunoregulatory (il-10) cytokines. The gene discussed is IL6; the disease is melanoma.