By relatively quantifying the intact N-glycopeptides between low and high levels of AFP tumor groups, several sialylated but not core fucosylated tri-antennary glycans were uniquely increased in HCC tumors with low AFP level, while many core fucosylated bi-antennary or hybrid glycans as well as bisecting glycans were uniquely increased in tumors with high AFP [22]. Here, AFP is linked to hepatocellular carcinoma.