Furthermore, it would appear that there is a subgroup of depressed patients who showed a low-grade inflammatory state (i.e., CRP > 3.0 mg/L) [29,47,61,69,74,80,83,86,100], corroborating the hypothesis that inflammation might contribute to developing some types of depression, but not all of them [75]. The gene discussed is CRP; the disease is major depressive disorder.