NF1 and tuberous sclerosis: Some other genetic syndromes have been already reported to be associated with both cellular radiosensitivity and mutations of cytoplasmic proteins; this is notably the case of Huntington’s disease (HD) [26], tuberous sclerosis (TSC) [27], neurofibromatosis type 1 (NF1) [28], and a subset of xeroderma pigmentosum D (XPD) [29].