Recent results indicate that AR is able to suppress the formation of a new HCC vascularization pattern (vasculogenic mimicry) by regulating the circRNA7/miR-7-5p/VE-cadherin/Notch4 (circulating RNA 7/miR7-5p/vascular endothelial cadherin/notch receptor 4) signalling axis in HCC cell lines. The gene discussed is NOTCH4; the disease is hepatocellular carcinoma.