In bladder cancer, Yang et al. demonstrated that AR decreased the transcription of miR-525-5p by binding to different AREs located at different positions of the miR-525-5p precursor promoter, which subsequently altered miRNA-525-5p/SLPI (secretory leukocyte peptidase inhibitor) signalling and increased cancer metastasis [59]. This evidence concerns the gene AR and urinary bladder cancer.