Dysfunctions in skeletal and cardiac muscles of DMD model mdx mice are significantly attenuated by partial restoration of dystrophin protein using the micro-dystrophin protein, which delivers a part of the cDNA copy of dystrophin to the affected tissues, based on internally deleted dystrophins [64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79]. This evidence concerns the gene DMD and Duchenne muscular dystrophy.