Interesting data come from the study of Aldeghaither et al., who successfully induced ADCC resistance in squamous carcinoma cell line (A431) highly expressing epidermal growth factor receptor (EGFR) by co-culture with NK92-CD16V cells and incubation with anti-EGFR mAb–cetuximab [59]. Here, EGFR is linked to squamous cell carcinoma.