SELE and acute kidney injury: Real-Time PCR analyses showed a reduction in the expression levels of specific markers of AKI, such as kidney injury molecule-1 (KIM1) and lipocalin 2/NGAL (LCN2), and of endothelial damage, such as E-selectin (SELE) and P-selectin (SELP), in the EV-treated AKI mice (Figure 6A,B).