Germline activating mutation of MERTK (also known as c-Mer) has been described in a single patient with MEN2-like phenotype (medullary thyroid carcinoma and PCC) and recurrent and metastatic PGL without the presence of germline mutation in the coding and splicing regions of RET or any other PPGL driver gene [44]. This evidence concerns the gene RET and adrenal gland pheochromocytoma.